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Auf dem Internationalen Hypnose-Kongress im Oktober in Bremen wird Prof. Irving Kirsch eine Vortrag über die angebliche Wirkung von Antidepressiva halten.
Hier der Abtract:
The Emperor's New Drugs: Medication and Suggestion in the Treatment of Depression
Lecture / Vortrag (30min)
Mittwoch, 17.10.2012
10:45 bis 17:45
Antidepressants are supposed to work by fixing a chemical imbalance, specifically, a lack of serotonin in the brain. Indeed their supposed effectiveness is the primary evidence for the chemical imbalance theory. But analyses of the published data and the unpublished data that were hidden by the drug companies reveals that most (if not all) of the benefits are due to the suggestion. Some antidepressants increase serotonin levels, some decrease it, and some have no effect at all on serotonin. Nevertheless, they all show the same therapeutic benefit. Even the small statistical difference between antidepressants and placebos may be an enhanced placebo effect, due to the fact that most patients and doctors in clinical trials successfully break blind. The serotonin theory is as close to any theory in the history of science having been proved wrong. Instead of curing depression, popular antidepressants may induce a biological vulnerability making people more likely to become depressed in the future.
Referent:
Prof. Dr. Irving Kirsch
Irving Kirsch is Associate Director of the Program in Placebo Studies at the Harvard Medical School, lecturer in medicine at Beth Israel Deaconess Medical Center, Professor of Psychology at the University of Plymouth (UK), and Professor Emeritus at the University of Hull and the University of Connecticut. He has published 10 books and more than 200 scientific journal articles and book chapters on placebo effects, antidepressant medication, hypnosis, and suggestion. He originated the concept of response expectancy. His meta-analyses on the efficacy of antidepressants were covered extensively in the international media and influenced official guidelines for the treatment of depression in the United Kingdom. His book, The Emperor’s New Drugs: Exploding the Antidepressant Myth, which has been published in English, French, and Japanese, was shortlisted for the prestigious Mind Book of the Year award. It was the topic of a 5-page cover story in Newsweek, and was favorably reviewed in the New York Review of Books by Marcia Angell, former editor-in-chief of the New England Journal of Medicine.
Hier der Abtract:
The Emperor's New Drugs: Medication and Suggestion in the Treatment of Depression
Lecture / Vortrag (30min)
Mittwoch, 17.10.2012
10:45 bis 17:45
Antidepressants are supposed to work by fixing a chemical imbalance, specifically, a lack of serotonin in the brain. Indeed their supposed effectiveness is the primary evidence for the chemical imbalance theory. But analyses of the published data and the unpublished data that were hidden by the drug companies reveals that most (if not all) of the benefits are due to the suggestion. Some antidepressants increase serotonin levels, some decrease it, and some have no effect at all on serotonin. Nevertheless, they all show the same therapeutic benefit. Even the small statistical difference between antidepressants and placebos may be an enhanced placebo effect, due to the fact that most patients and doctors in clinical trials successfully break blind. The serotonin theory is as close to any theory in the history of science having been proved wrong. Instead of curing depression, popular antidepressants may induce a biological vulnerability making people more likely to become depressed in the future.
Referent:
Prof. Dr. Irving Kirsch
Irving Kirsch is Associate Director of the Program in Placebo Studies at the Harvard Medical School, lecturer in medicine at Beth Israel Deaconess Medical Center, Professor of Psychology at the University of Plymouth (UK), and Professor Emeritus at the University of Hull and the University of Connecticut. He has published 10 books and more than 200 scientific journal articles and book chapters on placebo effects, antidepressant medication, hypnosis, and suggestion. He originated the concept of response expectancy. His meta-analyses on the efficacy of antidepressants were covered extensively in the international media and influenced official guidelines for the treatment of depression in the United Kingdom. His book, The Emperor’s New Drugs: Exploding the Antidepressant Myth, which has been published in English, French, and Japanese, was shortlisted for the prestigious Mind Book of the Year award. It was the topic of a 5-page cover story in Newsweek, and was favorably reviewed in the New York Review of Books by Marcia Angell, former editor-in-chief of the New England Journal of Medicine.