Ich hab mal pubmed und Google befragt und gefunden:
"Oral administrations of the acetone extract of ginger (which contains volatile oils and bitter substances) at 75 mg/kg, [6]-shogaol at 2.5 mg/kg, or a [6]-, [8]- or [10]-gingerol at 5 mg/kg enhanced the transport of a charcoal meal. The effects of these substances were similar to or slightly weaker than those of metoclopramide and donperidon."
Gastrointestinal motility enhancing effect of ginger and its active constituents. - PubMed - NCBI
MCP und Domperidon kenne ich zwar als die Peristaltik anregend, aber hier steht, dass Ingwer eine regulierende Wirkung hat:
"Bioactive compounds within the rhizome of ginger, particularly the gingerol and shogaol class of compounds, interact with several pathways that are directly implicated in CINV in addition to pathways that could play secondary roles by exacerbating symptoms. These properties include 5-HT3, substance P and acetylcholine receptor antagonism; anti-inflammatory properties; and
modulation of cellular redox signalling, vasopressin release,
gastrointestinal motility, and gastric emptying rate."
Ginger-Mechanism of Action in Chemotherapy-induced Nausea and Vomiting: A Review. - PubMed - NCBI
"The anticancer activity of ginger is attributed to its ability to modulate several signaling molecules like NF-κB, STAT3, MAPK, PI3K, ERK1/2, Akt, TNF-α, COX-2, cyclin D1, cdk, MMP-9, survivin, cIAP-1, XIAP, Bcl-2, caspases, and other cell growth regulatory proteins."
(
Ginger and its constituents: role in prevention and treatment of gastrointestinal cancer. - PubMed - NCBI)
Wenn's die modulieren kann, kann es sicher auch G-Proteine beeinflussen. Evtl. durch die Vanilloid-Rezeptoren?
Das ist mir gerade zu hoch, aber vielleicht checkt jemand mehr:
https://www.caymanchem.com/app/template/Article.vm/article/2116
(TRPV1: Pain, Peppers, and Prostaglandins)
Sorry dafür, dass das jetzt so viel Verschiedenes ist, ich hab zu wenig Ahnung davon, um sinnvoll vorzugehen.
